AccessToMedicines

Eisai ATM Navigator Making health available worldwide

Japanese / English
AccessToMedicines
Japanese / English

A Social Issue Neglected Tropical Diseases and Three Major Infectious Diseases

Elimination of Tropical Diseases

Neglected tropical diseases (NTDs) include 18 diseases that WHO (World Health Organization) identifies as tropical diseases that the human race must overcome. Prominent among them are lymphatic filariasis, Chagas’ disease, and dengue fever.
NTDs are endemic in 149 countries, infecting some 1 billion people and creating serious social difficulties. Among these countries, two NTDs are endemic in 100 countries and territories, while more than six NTDs are endemic in 30 countries and territories.
Although the spread of NTDs is mainly caused by poor hygienic conditions associated with poverty, this in turn leads to declines in the work force and productivity, thereby hampering efforts to escape from impoverished conditions. Infections from these diseases may result in serious physical impairment and this often results in normal economic and social activities becoming highly challenging to the individual. In the worst cases, NTDs may also result in the death of the patient. The prevalence of NTDs is a stumbling block to economic growth for developing and emerging countries and represents a serious issue for these regions.

For information on the number of NTD patients, see:
Number of Patients: Ten Neglected Tropical Diseases included in the London Declaration

CDC


What Are the 18 Neglected Tropical Diseases?

For details on these 18 diseases, please click on any of the boxes to open a new window.

References
WHO- Neglected Tropical Diseases April 2, 2015,
http://www.who.int/neglected_diseases/mediacentre/factsheet/en/

CDC- Neglected Tropical Diseases April 2, 2015,
http://www.cdc.gov/globalhealth/ntd/diseases/

See Details on Three Major Infectious Diseases

malaria
HIV/AIDS
tuberculosis

The London Declaration: A United Front to Eliminate and Eradicate NTDs

The first step toward eradicating NTDs was selecting target diseases to be eliminated and then launching an international united front of governments and pharmaceutical companies.
On January 30, 2012, 13 major pharmaceutical companies, the Bill & Melinda Gates Foundation, WHO, the U.K. and U.S. governments, the World Bank, and the governments of countries where neglected tropical diseases (NTDs) are endemic jointly issued the London Declaration, forming a united front to control and eliminate 10 of 17 WHO-designated NTDs by 2020 (see chart below). This is the largest international public–private sector partnership related to access to medicines. Participants aim to control and eliminate NTDs by tackling such issues as the supply and distribution of drugs and medical products, the development of treatment, and the consolidation of health and medical infrastructures. Subsequently, the quantity of drugs shipped to NTDs endemic countries has increased nearly 36 percent from 2011 (995 million) with nearly 1.35 billion doses provided free of charge in 2013.

Number of Patients: Ten Neglected Tropical Diseases included in the London Declaration
Disease Number of Patients
Worldwide
Number of Those
with Infection Risk
Blinding trachoma 84 million 600 million
Leprosy 400,000 -
Human African trypanosomiasis 300,000 60 million
Dracunculiasis 10,000 -
Lymphatic filariasis 120 million Approx. 1.3 billion
Chagas’ disease 8 to 9 million 25 million
The Leishmaniasis 12 million 350 million
Onchocerciasis 37 million 90 million
Schistosomiasis 207 million Approx. 800 million
Soil-transmitted helminthiasis
(collective term for diseases caused by roundworm, hook worm, and whipworm etc.)
Approx. 800 million
(registered as patients of ascariasis)
Approx. 4.2 billion
(registered as those with risk of ascariasis)
Number of Patients: Ten Neglected Tropical Diseases included in the London Declaration
Blinding trachoma
Number of Patients
Worldwide
84 million
Number of Those
with Infection Risk
600 million
Leprosy
Number of Patients
Worldwide
400,000
Number of Those
with Infection Risk
-
Human African trypanosomiasis
Number of Patients
Worldwide
300,000
Number of Those
with Infection Risk
60 million
Dracunculiasis
Number of Patients
Worldwide
10,000
Number of Those
with Infection Risk
-
Lymphatic filariasis
Number of Patients
Worldwide
120 million
Number of Those
with Infection Risk
Approx. 1.3 billion
Chagas’ disease
Number of Patients
Worldwide
8 to 9 million
Number of Those
with Infection Risk
25 million
The Leishmaniasis
Number of Patients
Worldwide
12 million
Number of Those
with Infection Risk
350 million
Onchocerciasis
Number of Patients
Worldwide
37 million
Number of Those
with Infection Risk
90 million
Schistosomiasis
207 million
Number of Those
with Infection Risk
Approx. 800 million
Soil-transmitted helminthiasis
(collective term for diseases caused by roundworm, hook worm, and whipworm etc.)
Number of Patients
Worldwide
Approx. 800 million
(registered as patients of ascariasis)
Number of Those
with Infection Risk
Approx. 4.2 billion
(registered as those with risk of ascariasis)

Source : Hotez et al. NEJM357:1010-1027,2007.

Eisai’s “Access to Medicines Activities”introductory pamphlet